osteopenia
Conditions
Interventions
1:healthy education
2:calcium 500mg, vitamin D 2000 IU
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Women over 65 years old, men over 70 years old; 2. Bone mineral density of lumbar spine (L1-4) or femoral neck or total hip showed that T value -2.5 to -1.0; 3. The subjects personally signed the informed consent form, indicating that they have been fully informed of the relevant contents of the research; 4. Subjects are willing and able to follow the research visit arrangements.
Exclusion criteria
Exclusion criteria: 1. any diseases known to affect bone metabolism or calcium metabolism, such as bone embolic diseases including osteomalacia, osteogenesis imperfecta and paget disease of bone; cushing syndrome; acromegaly;Parathyroid Diseases;thyroid disease;Malabsorption syndrome or any gastrointestinal diseases associated with malabsorption; abnormal calcium levels; rheumatoid arthritis; 2. Malignant tumor history in recent 5 years; 3. any medication history of anti-osteoporosis or known to affect bone metabolism, such as Bisphosphonate, Teripapeptide, selective estrogen receptor modulator; active vitamin D metabolites; glucocorticoid and the analogues; 4. medication history of Psychoactive drugs, substance abusers and dependents; 5. allergic history to the medication used in the study; 6. osteoporotic fractures history of distal forearm, hip, proximal humerus, vertebral, or X-ray examination inactive of vertebral fracture; 7. participation in other clinical studies within the first 3 months of subjects screening; 8. any other acute or chronic disorders not suitable for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| osteoportic fracture; | — |
Secondary
| Measure | Time frame |
|---|---|
| bone mineral density;bone turnover marker; | — |
Countries
China
Contacts
Public ContactZhen-Lin Zhang
Shanghai Sixth People's Hospital
Outcome results
None listed