Parkinson's disease
Conditions
Interventions
Gold Standard:MDS clinical diagnostic criteria for Parkinson’s disease
MRI 
in 
locus 
coeruleus 
and 
substantia 
nigra
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: The diagnosis of PD was made according to the Movement Disorder Society (MDS) clinical diagnostic criteria for Parkinsons disease and had not taken any medication .Patients meeting the diagnostic criteria for MSA,PSP,CBD,ET and Prodromal PD were also recruited.
Exclusion criteria
Exclusion criteria: 1. Participants were diagnosed as atypical parkinsonian syndromes such as drug-induced parkinsonism , vascular parkinsonism and normal pressure hydrocephalus; 2. Patients with evidence of brain damage or other neurological disorder; 3. History of PD,ET and other neurological/psychiatric disorders; 4. Unable to complete MRI examination, metal implants and claustrophobia in the body; 5. The image quality is not satisfied and quantitative analysis cannot be completed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diagnostic accuracy; | — |
Countries
China
Contacts
Public ContactJin Lirong
Zhongshan Hospital, Fudan University
Outcome results
None listed