Hepatocellular carcinoma, combined portal vein tumor thrombosis
Conditions
Interventions
Liver resection (LR):Liver resection
Sponsors
Third Affiliated Hospital of the Second Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Between 18-70 years; 2) Clinical diagnosis of hepatocellular carcinoma (clinical diagnostic criteria for hepatocellular carcinoma: meet the diagnostic criteria for primary liver cancer diagnosis and treatment in 2019); 3) Imaging (MR or CT) showed clear tumor thrombus, which did not reach the main portal vein and the contralateral side, (Cheng's classification I, II); 5) Have not received other anti-tumor treatments in the past; 6) Tumors and tumor thrombi are located on the same side of the liver and are resectable (the residual liver volume in patients without cirrhosis accounted for >30% of the standard liver volume, and in patients with cirrhosis, the residual liver volume accounted for > 40% of the standard liver volume; after evaluation Liver function can be compensated after surgery.) 7) ECOG 0-2; 8) Child-Pugh A; 9) Know the research process and agree to participate, sign relevant informed consent and other documents
Exclusion criteria
Exclusion criteria: 1) Have a history of other tumors; 2) The tumor thrombus exceeds the main portal vein or reaches the contralateral portal vein; 3) Combined with multiple metastases in the liver or distant metastases; 4) With portal hypertension (PLT<50*109/L, gastroscope suggests severe esophageal and gastric varices or a history of upper gastrointestinal bleeding, cavernous transformation of portal vein).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival;Median Survival Time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life Score;Adverse Events; | — |
Countries
China
Contacts
Public ContactZhou Weiping
Third Affiliated Hospital of the Second Military Medical University
Outcome results
None listed