Exploratory study of wearable low-intensity ultrasound in the disease progression of Amyotrophic lateral sclerosis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000035988

Enrollment

Unknown

Registered

2020-08-21

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amyotrophic lateral sclerosis

Interventions

experimental group:wearable low-intenstiy ultrasound + riluzole

control group:invalid ultrasound + riluzole

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with a diagnosis of probable or definite amyotrophic lateral sclerosis according to the El Escorial revised criteria 2. Disease duration = 36, normal FVC without obvious respiratory insufficiency; 5. Treatment with steady regimen of riluzole for a minimum of 1 month before study entry, and desiring its continuation; 6. Aged 18 years to 70 years; 7. Able to give informed consent, and written informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or nursing women; 2. History of seizures; 3. History of stroke of hemorrhage; 4. Severe head trauma in the past; 5. Cardiac pacemaker implantation; 6. Severe liver or kidney dysfunction; 7. Participate in other clinical trials.

Design outcomes

Primary

Measure	Time frame
MUNIX;	—

Secondary

Measure	Time frame
ALSFRS-R;MMT;CMAP;FVC;BMI;	—

Countries

China

Contacts

Public ContactXiaojie Zhang

Shanghai Sixth People's Hospital

xjzzhang@126.com+86 13917243532

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026