stroke
Conditions
Interventions
control group:Pseudostimulation + conventional rehabilitation
experimental group:Magnetic stimulation + conventional rehabilitation
Sponsors
Yueyang Integrative Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with ischemic stroke confirmed by clinical assessment and comprehensive imaging examination meet the diagnostic criteria for ischemic stroke; 2. Fugl-meyer score of motor function was confirmed as motor dysfunction; 3. Aged 18-70 years, men and women are not limited; 4. No cognitive impairment or communication impairment, MMSE score above 27; 5. The first onset was 2 days to 1 month.
Exclusion criteria
Exclusion criteria: 1. Patients with severe systemic diseases such as cardiopulmonary diseases and unable to tolerate rehabilitation treatment; 2. Diagnosed with mental illness, major depression (suicidal tendency) or epilepsy, family history of mental illness or epilepsy; 3. The presence of diabetes, uremia and other serious systemic diseases; 4. severe joint contracture; 5. Suffer from any reason leading to consciousness disorder; 6. According to the safety guidelines there are transcranial direct current/magnetic stimulation (TMS/tDCS) and functional magnetic resonance imaging (fMRI) check contraband such as: there is a metal foreign body or other electronic devices implanted in the body; 7. Auditory or visual impairments that may affect assessment and treatment; 8. Apply the drug that changes cerebral cortex excitability today (antiepileptic drug, sedative hypnotic kind medicaments).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change value of fugl-Meyer assessment of the affected upper limb.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body motor function: WOLF motor function score of upper limb, Fugl-Meyer motor function score;Evaluation of limb spasticity: Modified Ashworth score (MAS);Body balance ability: Berg balance scale;;Body balance ability: Berg balance scale;Daily life (behavioural) capacity: Common combination of the International Classification of Functioning, Disability and Health (ICF);Electrophysiological test of the affected upper limb: For tMS-MEP, central motor conduction time (CMCT), Silent Period;Functional MAGNETIC resonance Imaging (FMRI) included task-design BOLD scan, resting-state BOLD scan, brain structure phase scan and Diffusion Tensor Imaging (DTI).;Near Infrared Brain Functional Imaging (fNIRS); | — |
Countries
China
Contacts
Public ContactDongsheng Xu
Yueyang Integrative Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed