Acute Respiratory Distress Syndrome
Conditions
Interventions
ARDS patient group:no intervention
Non-ARDS patient group:no intervention
Sponsors
Renji Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Meet the diagnosis of severe pneumonia, the ARDS diagnosis meets the 2012 European Critical Care Association ARDS Berlin definition (JAMA 2012; 307:2526-2533); Berlin diagnostic criteria: 1. Acute onset: from known clinical damage to clinical diagnosis within 7 days; 2. Chest imaging: X-ray with bilateral diffuse infiltrates; 3. Oxygenation: PEEP>=5cmH2O, severity of the disease According to P/F>=300mmHg, it is mild; 200mmHg>=P/F>=100mmHg is moderate; P/F<=300mmHg is severe; 4.. Pulmonary edema: rule out pulmonary edema caused by insufficiency of the right heart.
Exclusion criteria
Exclusion criteria: 1. Severe hemodynamic instability; 2. Obvious bleeding tendency or active bleeding; 3. Pregnant and lactating women; 4. Tumors or other immune diseases; 5. Long-term use of immunosuppressants or immunocompromised.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Th17/Treg;Exosomal HS90 protein expression; | — |
Countries
China
Contacts
Public ContactJianxiao Chen
Renji Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed