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Effect of ephedrine and phenylephrine on sublingual microcirculation in elderly patients undergoing laparoscopic rectal cancer

Effect of ephedrine and phenylephrine on sublingual microcirculation in elderly patients undergoing laparoscopic rectal cancer

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035959
Enrollment
Unknown
Registered
2020-08-20
Start date
2019-08-18
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative hypotension

Interventions

group E :Sufentanil 0.5 µg/kg + propofol 1.5-2 mg/kg + cis-atracuramide 0.15 mg/kg was used for anesthesia induction, and sevoflurane (0.7-1.3 MAC) + remifentanil (0.05- 0.2 µg/kg/min) + cis-atracuram
group P:Sufentanil 0.5 µg/kg + propofol 1.5-2 mg/kg + cis-atracuramide 0.15 mg/kg was used for induction of anesthesia, mean arterial pressure was lower than 65 mmHg during induction and maintenance,

Sponsors

First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: Elderly patients aged 65 to 85 years old who require laparoscopic radical resection for colon cancer or rectal cancer; ASA grades I to II.

Exclusion criteria

Exclusion criteria: 1. Loose teeth, oral damage or bleeding, difficulty in opening the mouth and unable to perform sublingual microcirculation monitoring; 2. Hb=grade II; 4. two within three months Those undergoing second surgery; 5. refusing to sign informed consent.

Design outcomes

Primary

MeasureTime frame
Incidence of hypotensive adverse events;Influence of microcirculation under tongue;

Countries

China

Contacts

Public ContactJi Fuhai

First Affiliated Hospital of Soochow University

jifuhai@163.com+86 13656207331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026