Repairing bone defects with carbon quantum dots

Research on Carbon Quantum Dots in Repairing Bone Defects and Its Mechanism

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000035949

Enrollment

Unknown

Registered

2020-08-20

Start date

2020-09-01

Completion date

Unknown

Last updated

2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone defects

Interventions

Control group:Nil

Experimental group:Co-cultivation with carbon quantum dots or co-build bone defect repair materials

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. The age of the patients was 18-60 years old; 2. Both male and female patients were included; 3. Orthopedic patients who produce discarded cancellous bone during operation, such as hip osteoarthritis or femoral neck fracture undergoing hip replacement; patients with bone nonunion undergoing autologous iliac bone grafting and internal fixation; patients with lumbar disc herniation and lumbar spinal stenosis.

Exclusion criteria

Exclusion criteria: 1. Having a history of metabolic osteopathy or taking drugs affecting bone metabolism; 2. There was a history of diabetes and cancer; 3. Blood routine test, liver and kidney function and hepatitis were abnormal; Syphilis Serological Test and HIV antibody test were positive.

Design outcomes

Primary

Measure	Time frame
Characterization of carbon quantum dots;Cell differentiation ability;Bone defect repair ability;	—

Countries

China

Contacts

Public ContactLongxiang Shen

Shanghai Sxith People's Hospital

18930172617@163.com+86 18930172617

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026