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Application of circulating abnormal cell (CAC) detection in the differential diagnosis of benign and malignant pleural effusions

Application of circulating abnormal cell (CAC) detection in the differential diagnosis of benign and malignant pleural effusions

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035946
Enrollment
Unknown
Registered
2020-08-20
Start date
2020-09-01
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pleural effusion

Interventions

Gold Standard:cytological pathological testing
of&#32
(CAC)

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Clinical diagnosis of patients with pleural effusion, concurrent pleural effusion drainage; 2. Aged >=18 years; 3. The subject's pleural effusion undergoes cytology, tumor marker (CEA) testing, and other routine, biochemical, ADA and other auxiliary diagnostic tests; 4. Agree to participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Unable to puncture and drain pleural effusion; 2. Has received clinical therapeutic interventions related to lung cancer, such as surgery, radiotherapy, chemotherapy, targeted therapy, immunotherapy, etc.; 3. Local thoracic treatment, such as bevacizumab, lentinan, etc., has been performed within two weeks; 4. Due to sampling problems, it is unable to meet the research unit's pleural effusion cytological pathological testing requirements.

Design outcomes

Primary

MeasureTime frame
circulating abnormal cells;

Countries

China

Contacts

Public ContactTONG LIN

Zhongshan Hospital, Fudan University

radien@icloud.com+86 13764089607

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026