Benign tumor or lesion of the mandible
Conditions
Interventions
Case series:Osteotomy of mandible + Dental implant distractor combined with free fibular flap + Preparation tracheotomy
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years; 2. No restrictions on men or women; 3. Patients with benign tumor or lesion of the mandible requiring osteotomy of mandible; 4. Within 1 week before surgery, blood routine, coagulation function, liver function, renal function and ECG were normal (hemoglobin>80 g/L; absolute neutrophil count > 1.5 x 10^9/L, platelet > 100 x 10^9/L; bile red = 50 ml/min); 5. Maxillofacial enhanced CT and panoramic film were performed one week before surgery; 6. No organic lesions of important organs, suitable for general anesthesia; 7. Postoperative radiotherapy and chemotherapy are not required.
Exclusion criteria
Exclusion criteria: 1.Complicated with other malignant tumor or recurrence of or primary tumor within 5 years; 2. History of severe drug allergy; 3. Patients with pregnancy, lactation or neurological disorders; 4. Patients who have participated in other clinical trials; 5. Patients who have received radiotherapy, chemotherapy and targeted drugs and other anti-tumor treatments before surgery; 6. Mouth opening < 3.5cm; 7. Contraindications associated with general anesthesia surgery (such as hypertension, diabetes etc, which are difficult to control with drugs); 8. Patients with congenital immune deficiency or organ transplantation; 9. Patients with diseases related to HBV, HCV, HIV, TRUST, etc..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone healing;Degree of wound healing;Postoperative complications;Primary lesion condition; | — |
Countries
China
Contacts
Public ContactChenping Zhang
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed