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A single-center randomized controlled trial for comparing the efficacy and safety of thulium laser endoscopic en bloc resection followed by internal iliac artery infusion chemotherapy and radiotherapy with radical cystectomy for T2 phase muscle invasive bladder cancer patients

A single-center randomized controlled trial for comparing the efficacy and safety of thulium laser endoscopic en bloc resection followed by internal iliac artery infusion chemotherapy and radiotherapy with radical cystectomy for T2 phase muscle invasive bladder cancer patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035915
Enrollment
Unknown
Registered
2020-08-20
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder cancer

Interventions

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) The patient was pathologically diagnosed as T2 muscular invasive bladder cancer; (2) Imaging examination revealed no lymph node metastasis or distant metastasis of bladder cancer; (3) Agreeing to comprehensive bladder preservation treatment and can be followed up on time after treatment; (4) Organs (heart, liver, lung, kidney) function is basically normal, PS score: 0-2; (5) Bladder capacity >=200ml.

Exclusion criteria

Exclusion criteria: 1. The history of abdominal and pelvic radiation therapy; 2. Metastatic bladder cancer or other cancer involving the bladder; 3. Those who are allergic to iodine; 4. Pregnant women or lactation patients.

Design outcomes

Primary

MeasureTime frame
Disease-free survival in two years;

Secondary

MeasureTime frame
EORTC Quality of Life Questionnaire;Disease-specific survival in three and five years;Overall survival survival in three and five years;

Countries

China

Contacts

Public ContactLiu haitao

Shanghai General Hospital

doctorlht69@163.com+86 15301655608

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026