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The Efficacy of Early Prone or Lateral Positioning in Severe COVID-19 Patients: a Single-Center Prospective Cohort Study

The Efficacy of Early Prone or Lateral Positioning in Severe COVID-19 Patients: a Single-Center Prospective Cohort Study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035907
Enrollment
Unknown
Registered
2020-08-19
Start date
2020-01-31
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel coronavirus pneumonia (COVID-19)

Interventions

Prone vs. Lateral Positioning:Nil

Sponsors

Department of Respiratory and Critical Care Medicine,West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. patients with novel coronavirus infection have been diagnosed. 2. One of the following standards is met: (1) Dyspnea, respiratory rate (RR) >= 30 breaths / min; (2) At rest, pulse oxygen saturation <= 93%, or the ratio of PaO2 to FiO2 <= 300 mmHg; 3. Chest CT showed bilateral or unilateral lung back or peripheral exudation, consolidation of patients.

Exclusion criteria

Exclusion criteria: 1. Patients younger than 18 years old or over 80 years old were excluded; 2. The object of pregnancy; 3. Critical patients (invasive mechanical ventilation, severe heart failure or hemodynamic instability); 4. Patients with contraindication of prone position or lateral position (such as history of vertebral body disease); 5. Subjects that cannot be matched.

Design outcomes

Primary

MeasureTime frame
SpO2/FiO2;ROX index;Borg scale;NEWS2 score;

Secondary

MeasureTime frame
length of hospital stay;time to Virus shedding;Time to clinical improvement;Rate of intubation avoidance;

Countries

China

Contacts

Public ContactLiu Dan

West China Hospital of Sichuan University

liudan10965@wchscu.cn+86 18980605965

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026