Skip to content

Early Prevention Strategies of Severe Proliferative Vitreoretinopathy base on Precision Diagnosis of Single Cell Sequencing

Early Prevention Strategies of Severe Proliferative Vitreoretinopathy base on Precision Diagnosis of Single Cell Sequencing

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035904
Enrollment
Unknown
Registered
2020-08-19
Start date
2020-09-01
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhegmatogenous retinal detachment

Interventions

3:Conventional Surgery for Retinal Detachment,RPE cell collection, single cell heterogeneity study, postoperative intervention
1:Conventional Surgery for Retinal Detachment
2:Conventional Surgery for Retinal Detachment,RPE cell collection, single cell heterogeneity study

Sponsors

Shanghai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18-60 years old; (2) Patients with rhegmatogenic retinal detachment (RRD); (3) Surgery for Retinal Detachment is required; (4) Myopia < = 800 degrees; (5) PVR classification: no restrictions; (6) Patients undergoing the first or second operation. (7) Patients volunteered to participate in this study and signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Cant meet the inclusion criteria; (2) Those who are allergic to the drugs used in the study; (3) Combined with other eye diseases: other fundus diseases, glaucoma, corneal opacity diseases, genetic diseases); (4) history of internal eye surgery >=3 times; (5) Postoperative follow-up could not be scheduled; (6) Patients with systemic diseases (such as asthma, heart failure, myocardial infarction, liver failure, kidney failure and other major diseases).

Design outcomes

Primary

MeasureTime frame
Number of participants who achieved retina reattachment;Number of participants who occurred severe PVR;Best Corrected visual Acuity (BCVA;

Countries

China

Contacts

Public ContactFang Wang

Shanghai Tenth People's Hospital

18917683335@163.com+86 18917683335

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026