Alzheimer's disease
Conditions
Interventions
Gold Standard:Clinical outcome based on the PET scan
Index test:Simoa 
technology 
in 
and 
protein 
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants are willing to sign an informed consent form, aged 50 to 80 years; no anxiety, depression and other mental disorders in the past month, normal hearing and vision, cooperation in cognitive examination, no contraindications to complete MRI. MRI examination of the head showed only varying degrees of brain atrophy, without lacunar infarction, patchy or diffuse leukoaraiosis.
Exclusion criteria
Exclusion criteria: A clear history of stroke, brain tumors, hydrocephalus, brain trauma and other brain diseases, serious physical diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peripheral blood A beta 40;The levels of Aß42 in peripheral blood;T-tau levels in peripheral blood;P-tau levels in peripheral blood;;Nfl level in peripheral blood;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactGuo Qihao
Shanghai Sixth People's Hospital
Outcome results
None listed