The optimized design and accurate clinical examination of periodontal membrane scaffolds

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000035886

Enrollment

Unknown

Registered

2020-08-19

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontitis

Interventions

Control Group:No scaffold on the root surface

Experiment Group:root surface was covered by the dECM scaffold

Individual Experiment Group:root surface was covered the individual dECM scaffold

Eligibility

Sex/Gender

All

Age

25 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Patients with periodontitis, aged 25-40 years; 2. Informed consent; 3. Arch crowding <=4mm; 4. No TMD; 5. Patients are generally in good condition.

Exclusion criteria

Exclusion criteria: 1. Tooth mobility III° after initial periodontic treatment; 2. Patients with cleft lip and palatal; 3. TMD; 4. Patients with severe heart, lung, kidney, liver dysfunction and metabolic diseases.

Design outcomes

Primary

Measure	Time frame
Alveolar bone height;attachment level;buccal vertical bone level;buccal bone thickness ;	—

Countries

China

Contacts

Public ContactBingjiao Zhao

Department of Orthodontics, Shanghai Stomatological Hospital

joyce_zhao_ortho@fudan.edu.cn+86 13818228184

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026