Hirayama disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: For Hirayama disease: 1. Male patients; 2. Aged 14 to 25 years old; 3. Right-handed; 4. The clinical diagnosis of Hirayama disease and Huashan is clear; 5. Voluntarily participate in the study and sign an informed consent. For healthy control: 1. Male; 2. Aged 14-25 years old; 3. Right-handed; 4. Voluntarily participate in the research and sign an informed consent.
Exclusion criteria
Exclusion criteria: 1. Participate in other clinical research at the same time; 2. Combined with cubital tunnel syndrome, carpal tunnel syndrome and other peripheral nerve compression or injury diseases; 3. Combined with craniocerebral trauma, history of surgical treatment; 4. Combined with other disease in nerve system such as epilepsy, Parkinson; 5. History of chronic diseases such as diabetes, severe cardiopulmonary dysfunction, etc.; 6. Contraindications in MRI examinations such as claustrophobic syndrome and metal device placement in the body.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FA value of DTI;ADC value of DTI;bilateral activation in the primary motor area;bilateral activation in the SMA;Grip strength;DASH score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Spinal cord dysfunction affected segment;Cortical activation area; | — |
Countries
China
Contacts
Huashan Hospital Fudan University