Sepsis, SLE, JA, hematological malignancies, transplantations (marrow, kidney, liver), refractory epilepsy, refractory nephrotic syndrome
Conditions
Interventions
Infection:Anti-infective drugs
Autoimmune diseases:Immunosuppresants
Transplantation:Immunosuppressants
Refractory diseases:Anti-epileptics, immunoregulants
Sponsors
Children's Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: (1) diagnosed as one of the four types of the diseases: infection (sepsis of newborn/premature), autoimmune diseases (systemic lupus erythematosus, juvenile arthritis, hematological malignancies); (2) aged 0~18 years; (3) used the specific drugs to treat the diseases; (4) administered the drugs via the specific ways.
Exclusion criteria
Exclusion criteria: 1. have severe inborn defects; 2. have HIV infection or have HIV-infected mothers; 3. critically-ill and cannot survive through the study period; 4. allergic to the study drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma drug concentration; | — |
Countries
China
Contacts
Public ContactZhiping Li
Children's Hospital of Fudan University
Outcome results
None listed