Stroke
Conditions
Interventions
Gold Standard:The diagnosis of cerebral infarction was based on the diagnostic criteria adopted by the Fourth National Cerebrovascular Academic Conference, and was confirmed by MRI or CT.
Index test:1. 
Examination 
of 
the 
and 
arteries
2. 
contrast-enhanced 
ultrasound 
Sponsors
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: LAA group: 1. The first cerebral infarction occurred and the onset was less than 7 days; 2, The TOAST classification of acute ischemic stroke was LAA; 3. The thickness of carotid soft plaque was more than 2mm. Control group: 1. Subjects with no history of cardiovascular and cerebrovascular events (no clinical symptoms group); 2. Carotid artery soft plaque thickness> 2mm.
Exclusion criteria
Exclusion criteria: 1. Contraindications to the use of ultrasound contrast agents, such as unstable angina, acute heart failure, and acute endocarditis; 2. Transient ischemic attack; 3. Persons with known ultrasound contrast agent allergy; 4. Recent active bleeding History, or accompanied by malignant tumors, blood diseases, severe liver, lung, and kidney diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intima media thickness;Pulse wave velocity;Accuracy ratio;Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactZhaojun Li
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed