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Effect of gender on the effective dose of fentanyl in inhibiting the reaction of painless bronchoscopy

Half effective dose and 95% effective dose of fentanyl combined with propofol in painless bronchoscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035855
Enrollment
Unknown
Registered
2020-08-18
Start date
2020-08-31
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing bronchoscopy

Interventions

Case series:The bronchoscopy response was suppressed with alfentanil

Sponsors

Taizhou Hospital of Zhejiang Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients who received tracheoscopy for the first time; 2. Patients with ASA grade I-II; 3. Aged 18-70 years, regardless of gender.

Exclusion criteria

Exclusion criteria: Those with any of the following were excluded from the study 1. Patients with contraindication of bronchoscopy; 2. Patients with opioid allergy; 3. Patients with severe airway stenosis and acute infection; 4. Arrhythmia (1) Sinus bradycardia with ventricular rate < 45 beats / min was negative in atropine test; (2) Grade II and above atrioventricular block or ventricular block; or other arrhythmias with high risk of sinus arrest, such as sick sinus syndrome (SSS). 5. Patients with severe cardiac insufficiency: NYHA class III or above; 6. Patients with liver dysfunction: abnormal biochemical indexes of liver function (see 7.1 for indicators and normal range); 7. Women in labor, childbirth or lactation period; 8. Patients whose preoperative state of consciousness was difficult to complete independently and accurately; 9. Patients with a history of psychotropic drug use; And / or meet any other conditions considered by the researchers as unsuitable for inclusion in the study.

Design outcomes

Primary

MeasureTime frame
Bronchoscope score;Oxygen saturation;

Secondary

MeasureTime frame
Effectiveness of heart rate systolic pressure product (RPP) control;Nausea and vomiting;

Countries

China

Contacts

Public ContactMingcang Wang

Department of Anesthesiology, Taizhou hospital, Zhejiang Province

wangmc@enzemed.com+86 13757616856

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026