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Risk groups for predicting recurrence free survival in non-muscle-invasive bladder cancer patients treated with bacillus Calmette–Guerin based on the exon sequencing analysis and inflammatory factors

Risk groups for predicting recurrence free survival in non-muscle-invasive bladder cancer patients treated with bacillus Calmette–Guerin based on the exon sequencing analysis and inflammatory factors

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035848
Enrollment
Unknown
Registered
2020-08-18
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bladder cancer

Interventions

Case series:None

Sponsors

Fudan University Shanghai Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. TURB/re-TURB postoperative pathology identified NMIBC; 2. aged 18~80 years old; 3. ECOG score 0-1; 4. Received postoperative BCG bladder perfusion treatment; 5. Informed consent was signed by individual patients; 6. Enrolled patients agreed to refuse other bladder cancer treatment.

Exclusion criteria

Exclusion criteria: 1. TURB/re-TURB postoperative pathological confirmation of MIBC; 2. Other malignant tumor disease history; 3. Acute infection of various pathogens or chronic inflammatory diseases; 4. Congenital or acquired immunodeficiency; 5. Severe systemic or chronic expendable diseases (diabetes, cardiovascular disease and liver and kidney dysfunction); 6. Blood system diseases or taking drugs affecting hematopoietic function; 7. Chemoradiotherapy or biotherapy history; 8. Involved in other clinical trials; 9. Other circumstances considered unsuitable by researchers (e.g. mental disorders).

Design outcomes

Primary

MeasureTime frame
Exon mutation;

Secondary

MeasureTime frame
Inflammatory indicators;

Countries

China

Contacts

Public ContactYi-Ping Zhu

Fudan University Shanghai Cancer Center

fudanzhuyiping@163.com+86 Yi-Ping Zhu

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026