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Establishment of two scoring system for early identification and intervention evaluation of bloodstream infection respectively based on emerging biomarkers with usefulness validation in clinical trial.

Establishment of two scoring system for early identification and intervention evaluation of bloodstream infection respectively based on emerging biomarkers with usefulness validation in clinical trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035843
Enrollment
Unknown
Registered
2020-08-18
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Stream Infection

Interventions

Experimental group:Empirical anti-microbial therapy under the guidance of early identification and treatment efficacy evaluation model
Control Group:Routine treatment of bloodstream infection

Sponsors

Huashan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Volunteer to participate in this experiment and willing to sign the informed consent; 2. Aged >=18 years old; 3. Blood stream infection is suspected clinically, and blood culture is performed; 4. Etiological results have not yet been obtained; 5. Systemic anti-microbial therapy has not been initiated.

Exclusion criteria

Exclusion criteria: 1. Patients with disseminated infection (such as abscess, endocarditis); 2. Feverish patients with granulocytopenia; 3. Those who suffer from severe underlying diseases and have an estimated survival time of less than 1 month; 4. Researchers believe that there may be any circumstances that increase the risk of subjects or interfere with clinical research.

Design outcomes

Primary

MeasureTime frame
30-day all-cause mortality;

Secondary

MeasureTime frame
Cure rate of bloodstream infection;Days of anti-bacterial treatment for bloodstream infection;Usage of antimicrobials;Hospitalization days since the onset of blood stream infection;

Countries

China

Contacts

Public ContactHaihui Huang

Institute of Antibiotics, Huashan Hospital, Fudan University

huanghaihui@fudan.edu.cn+86 13916685836

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026