melasma
Conditions
Interventions
Case series:Subjects' hemiface was injected into the dermis with non-crosslinked hyaluronic acid combined with 2% tranexamic acid injection for injection. Control hemiface was injected into the dermis
Sponsors
Shanghai Dermatology Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Chinese female or male; (2) Aged 18-50 years old; (3) The subject has moderate to severe melasma; (4) Be able to understand and follow the study requirements and follow the study protocol during the whole study period; (5) Subjects voluntarily participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Pregnancy; (2) Operator currently undergoing or planning to undergo medical treatment or cosmetic surgery; (3) The face has been exposed to unprotected direct sunlight or artificial ULTRAVIOLET light for at least 2 hours recently; (4) Allergic to any component in the test product; (5) Those who have used other means to treat melasma within 14 days (6) Participated in any other clinical research project within 30 days before the study; (7) Other conditions that the researcher considers not appropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melanin index;Cuticle moisture content;Transepidermal moisture loss rate; | — |
Countries
China
Contacts
Public ContactXu Sijia
Department of Medical Cosmetology, Shanghai Dermatology Hospital
Outcome results
None listed