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Clinical effect of high branched chain amino acid corn oligopeptide on hepatitis Cirrhosis: a randomized controlled trial.

Clinical effect of high branched chain amino acid corn oligopeptide on hepatitis Cirrhosis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035815
Enrollment
Unknown
Registered
2020-08-17
Start date
2020-09-01
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatic cirrhosis

Interventions

Corn peptide high dose group:High dose corn peptide
Corn peptide low dose group:Low dose corn peptide

Sponsors

The Affiliated Hospital of Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with liver cirrhosis were diagnosed clinically; 2. The age ranged from 30 to 65 years old; 3. The total score of nutritional risk screening 2002 (NRS-2002) was more than 3 points, or the mini nutritional assessment (MNA) of inpatients was less than 24 points, indicating malnutrition; 4. The child Pugh grade was B and C; 5. Patients who met the indications of oral enteral nutrition support, voluntarily participated and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe organic diseases of cardiovascular, brain, lung, kidney and other important organs; 2. Patients with end-stage liver cirrhosis complications such as massive hemorrhage of upper gastrointestinal tract, hepatic encephalopathy, hepatorenal syndrome, etc.; 3. Mental illness patients, pregnant or lactating women; 4. Patients with severe endocrine and immune system diseases; 5. Patients who use albumin, plasma preparations and other drugs to promote plasma albumin production.

Design outcomes

Primary

MeasureTime frame
Liver function indexes;Blood coagulation indexes;Imaging indexes;

Secondary

MeasureTime frame
Lipid metabolism indexes;

Countries

China

Contacts

Public ContactHan Lei

The Affiliated Hospital of Qingdao University

yy9226@126.com+86 18661809226

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026