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An exploratory study on biomarkers for predicting the outcome of antidepressant treatment

A study on biomarkers for predicting the outcome of antidepressant treatment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035811
Enrollment
Unknown
Registered
2020-08-17
Start date
2020-09-01
Completion date
Unknown
Last updated
2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

case series:Nil

Sponsors

Peking University Sixth Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The patients were diagnosed according to the dsm-5 diagnostic criteria for depressive episode and the Chinese version of mini; 2. The patients with first attack or relapse have not taken antidepressant drugs or have not taken antidepressant drugs this time; 3. Inpatients or outpatients; 4. Patients aged 18-65 years old, regardless of gender; 5. Patients who have signed the informed consent form; 6. Patients with HAMD score >= 17; 7. Patients with hama-14 score < 14.

Exclusion criteria

Exclusion criteria: 1. Patients who meet the dsm-5 diagnostic criteria for any other mental disorder other than depression and the Chinese version of mini for any other mental disorder; 2. Patients with a history of any other mental illness; 3. Patients with cognitive impairment or personality disorder; 4. Patients who met the dsm-5 criteria for substance abuse or dependence in the past 6 months; 5. Patients with serious physical diseases, such as heart disease (i.e. grade II and above cardiac function) or basal heart rate 140mmHg; diastolic blood pressure 90mmHg; obvious abnormal liver and renal function (transaminase >= 3 times of the upper normal limit).

Design outcomes

Primary

MeasureTime frame
HAMD;

Secondary

MeasureTime frame
HAMA;PANSS;SRRS;

Countries

China

Contacts

Public ContactLi Suxia

Peking University

li313@bjmu.edu.cn+86 13581750199

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026