Respiratory Microecology and Risk Factors in Patients with Acute Lung Injury Induced by Aspiration Pneumonia

Correlation of the Lower Respiratory Tract Microflora and its Inflammatory Response in Patients with Aspiration Pneumonia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000035806

Enrollment

Unknown

Registered

2020-08-17

Start date

2020-09-01

Completion date

Unknown

Last updated

2020-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aspiration pneumonia

Interventions

control group:Nil

aspiration pneumonia group:Nil

Aspiration pneumonia to ALI group:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 80 years. 2. Comply with the Diagnostic Criteria of aspiration pneumonia. 3. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Pneumonia caused by pathogen infection. 2. Patients with other systemic infections. 3. Previous history of severe heart, lung, liver, kidney and other important organ dysfunction. 4. Patients with malignant tumors, long-term use of immunosuppressive agents or immunodeficiency. 5. Other reasons: not suitable to participate in this study.

Design outcomes

Primary

Measure	Time frame
Oral microbiological testing;Sputum microbiological testing;Inflammatory factors;anti-inflammatory cytokines;Blood routine;C-reactive protein;Procalcitonin;Coagulation function;Blood glucose;Immune function;Acute Physiology and Chronic Health Evaluation II, APACHE II;Glasgow Coma Score, GCS;	—

Secondary

Measure	Time frame
Hospital stay;Prognosis;	—

Countries

China

Contacts

Public ContactDaikun He

Jinshan Hospital, Fudan University

daikun_he@126.com+86 18930819939

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026