ED caused by radical prostatectomy
Conditions
Interventions
Experimental group:receive small dose PDE5 inhibitor + Low-Intensity Extracorporeal Shockwave Therapy
Control group:receive small dose PDE5 inhibitor
Sponsors
Fudan University Shanghai Cancer Center
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. The patients who received nerve-sparing radical prostatectomy; 2. The surgeon who have conducted more than 100 radical prostatectomy one year and mastered bilateral standard Walsh nerve-sparing radical prostatectomy; 3. Aged 40 to 70 years and had normal sexual function; 4. The pTNM satge was pT2 or earlier stage; 5. The patients did not receive PDE5i 4 weeks before incusion; 6. The patients have stable physical relationship, and tried sextual activity more than 3 times; 7. The patients shoud not receive the other ED treatment during the study and follow-up period.
Exclusion criteria
Exclusion criteria: 1. Any instable mental disease, spinal injuries, and penile anatomic abnormality; 2. Have other cancers within 5 years; 3. Chronic blood systemic diseases; 4. Instable blood pressure(systolic blood pressure>160mmHg and diastolic blood pressure>100mmHg); 5. Instable blood glucoseHbA1c>13%; 6. Receive ADT therapy; 7. Receive pelvic radiotherapy; 8. Severe coagulopathy and receive anticoagulants(such as coumadin); 9. The researchers did not think the patients were suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The result of NPTR; | — |
Countries
China
Contacts
Public ContactSu Hengchuan
Fudan University Shanghai Cancer Center
Outcome results
None listed