medulloblastoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a) Age> 3 years old, no gender limit; b) Surgical pathology diagnosed as medulloblastoma; c) Traditional molecular typing is WNT/SHH type; d) The auxiliary classification of small molecule metabolism detection is WNT/SHH type; e) The clinical risk is classified as standard risk group; f) KPS score =70; g) Expected survival time = 3 years; h) Have not received any other radiation and chemotherapy in the past; i) The subject voluntarily joins the study, and the patient or legal guardian signs an informed consent form with the consent of the patient, with good compliance and cooperation with follow-up.
Exclusion criteria
Exclusion criteria: a) Relapsed patients; b) Past or simultaneous suffering from other malignant tumors; c) According to the judgment of the investigator, there are other patients with concomitant diseases that seriously endanger the safety of the patient or affect the completion of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse events;OS; | — |
Countries
China
Contacts
Xinhua Hospital, Shanghai Jiao Tong University