The effect evaluation of pretreatment with different dose of dexamethasone to preventing the etomidate-induced myclonus: a randomized controlled trial.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000035765

Enrollment

Unknown

Registered

2020-08-16

Start date

2020-08-15

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myoclonus

Interventions

Group 1:dexamethasone, 0.1mg/kg

Group 2:dexamethasone, 0.2mg/kg

Group 3:dexamethasone, 0.3mg/kg

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: A total of 200 patients, aged 18-65 years old, with ASA grade I-II and body mass index (BMI) of 18-28kg/m2, were selected to undergo painless colonoscopy or treatment within 30 Minutes.

Exclusion criteria

Exclusion criteria: Cardiopulmonary and brain diseases, epilepsy, neuromuscular transmission disorders and psychiatric diseases, hypertension, liver and kidney impairment, adrenocortical dysfunction, constraints for etomidate or dexamethasone, use of drugs that affect cardiovascular function.

Design outcomes

Primary

Measure	Time frame
The incidence of myoclonus;	—

Secondary

Measure	Time frame
Mean arterial pressure;The incidence of adverse event;	—

Countries

China

Contacts

Public ContactYang Xiao-Lin

North Sichuan Medical College

yang_xl_yang@126.com+86 13990826183

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026