Clinical study of extracorporeal membrane oxygenation technology to improve the therapeutic outcome of congenital tracheal stenosis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000035739

Enrollment

Unknown

Registered

2020-08-16

Start date

2021-01-01

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital tracheal stenosis

Interventions

ECMO group:Application of ECMO technology in surgery

CPB group:Application of CPB technology in surgery

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1) All children diagnosed with CTS; 2) Gestational age >= 32 weeks, weight >= 2000g; 3) No serious infection before surgery; 4) No history of rescue before surgery.

Exclusion criteria

Exclusion criteria: 1) There are serious multiple organ dysfunction before operation; 2) Congenital heart disease with intracardiac anatomical deformities (such as VSD / ASD / TOF, etc.) needs to be corrected during the same period during operation; 3) ECMO support technology is rejected.

Design outcomes

Primary

Measure	Time frame
TNF-a;IL-2, IL-6, IL-8, IL-10;AT;	—

Secondary

Measure	Time frame
Hospital mortality rate;Complication rate;Ventilator parameters;Ventilator time;ICU time;amount of bleeding;Positive inotropic drug score;cardiac output;ejection fraction;Creatinine;urine volume;renal area NIRS value;Lactic acid;tandard bicarbonate concentration;aminotransferase;glutamyl transpeptidase;Glial fibrillary acidic protein;	—

Countries

China

Contacts

Public ContactYinyu Yang

Shanghai Children's Medical Center, affiliated to Shanghai Jiaotong University

yangyinyu@scmc.com.cn+86 18930830953

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026