Portal Hypertension
Conditions
Interventions
Sponsors
Zhongshan Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The gender of the patient is not limited, aged 18 to 75 years old; 2. Clinically or pathologically diagnosed liver cirrhosis; 3. A history of rupture of esophageal and gastric varices confirmed by endoscopy, and bleeding again after receiving standard treatment; 4. Child A or B grade of liver function; 5. Platelet count >=50x10^9/L; 6. Prothrombin time (PT) does not exceed the upper limit of the normal control for 3 seconds; 7. Serum creatinine concentration <=115umol/L; 8. The patient and family members agree to join the clinical trial and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Imaging confirmed extensive thrombosis in the portal system; 2. Those who have previously received portal hypertension surgery related treatments (including: splenectomy, surgical devascularization or shunt, etc.); 3. Those with any malignant tumor; 4. Pulmonary artery pressure>40mmHg, left ventricular ejection fraction =100, total bilirubin> 51umol/L that fails to improve after symptomatic treatment; combined with active infection, especially inflammation of the biliary system; female patients are pregnant Or breastfeeding; severe contrast agent allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time-to-peak;Peak Height;AUC; | — |
Countries
China
Contacts
Public ContactJingqin Ma
Zhongshan Hospital of Fudan University
Outcome results
None listed