Pediatric non-cardiac surgery
Conditions
Interventions
Study group:Coinfusion of esketamine with propofol
Control group:Infusion of propofol alone.
Sponsors
Affiliated Hospital of Capital Institute of Pediatrics
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Age between 2 to 6 years, both sexes, children with ASA classfication I or II undergoing elective surgery with total intravenous venous anesthesia; 2. Expected Operative time less than 60 min; 3. Operation types include general, urology, orthopedics, otorhinolaryngologic, ophthalmic surgery.
Exclusion criteria
Exclusion criteria: 1. Combined with Liver, renal, central nervous system, and metabolic disease; 2. Allergies to propofol, ketamine, opioids, and muscle relaxants; 3. With previous history of anesthesia and surgery; 4. Refused to participate in.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FLACC pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic variables;Bispectral index;Dosing of anesthetics;Time to extubation;Time to eye opening;return of consciousness;length of stay in PACU;pediatric anesthesia emergence delirium scale;Dosing of analgesics and sedatives in PACU;Nausea and vomiting;Psychopathological symptoms;preventive postoperative analgesics;oropharyngeal airway usage;frequency of rescue opioid use; | — |
Countries
China
Contacts
Public ContactShoudong Pan
Affiliated Hospital of Capital Institute of Pediatrics
Outcome results
None listed