gastric cancer
Conditions
Interventions
observation group:modified proximal gastrectomy plus residual-gastroesophageal anastomosis
control group:total gastrectomy
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Histologically confirmed adenocarcinoma (biopsy by endoscopy before surgery); (2) The lesion is confined to the proximal 1/3 of the stomach, cT1-2N0M0 according to the AJCC (8th edition); or adenocarcinoma of the esophagogastric junction according to the Japanese Gastric Cancer Treatment Guideline (15th edition), and the length is less than 4 cm; (3) From 18 to 90 years old; (4) ECOG 0-2, ASA I-III; (5) Patients who received non-curative endoscopic surgery confirmed by pathology and need additional surgery can be included in this study; (6) Informed consent obtained; (7) Open surgery and laparoscopic surgery are both acceptable.
Exclusion criteria
Exclusion criteria: (1) Patient who received any anti-tumor treatment (chemotherapy, radiotherapy, targeted drug treatment, etc.) after being diagnosed with gastric cancer; (2) Patient who is participating in or has participated in other clinical studies in the past six months; (3) Vulnerable groups ; (4) Patient who suffers from a serious mental illness; (5) Patient who suffers from other malignant tumors within five years; (6) Pregnant women, lactating women, and those planning to become pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of reflux esophagitis within postoperative 1 year; | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptoms of esophageal reflux;postoperative quality of life;complications of surgery;nutritional status;oncological efficacy; | — |
Countries
China
Contacts
Public ContactSHU PING
Zhongshan Hospital, Fudan University
Outcome results
None listed