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The predictive utility of ABC Score for the antiplatelet effect of clopidogrel in patients with coronary artery disease

The predictive utility of ABC Score for the antiplatelet effect of clopidogrel in patients with coronary artery disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035690
Enrollment
Unknown
Registered
2020-08-16
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Interventions

Case series:No

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Two thousand consecutive patients with coronary heart disease confirmed by coronary angiography and received coronary intervention, were collected. All of them received 300mg aspirin and 300mg clopidogrel the day before coronary angiography.

Exclusion criteria

Exclusion criteria: 1. Taking cilostazol, tirofiban, or ticagrelor at the same time; 2. Taking oral anticoagulation drugs such as warfarin at the same time; 3. Contraindications to the use of aspirin or clopidogrel; 4. Serious complications (coronary dissection, pericardial tamponade, cardiogenic shock, ventricular fibrillation, etc.) occurred during coronary intervention. 5. Platelets less than 100 x 10^9/L; 6. Patients with hematologic disease or high risk of bleeding; 7. Patients with malignant tumor; 8. Pregnant women; 9. Patients with severe renal insufficiency; 10. Patients with impaired liver function.

Design outcomes

Primary

MeasureTime frame
high residual platelet reactivity, HRPR;

Secondary

MeasureTime frame
peri-procedure myocardial injury, PMI;

Countries

China

Contacts

Public ContactWu Hongyi

Zhongshan Hospital, Fudan University

wu.hongyi@zs-hospital.sh.cn+86 13817165522

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026