Colorectal cancer
Conditions
Interventions
Case series:closely follow-up after blood collection
Sponsors
Fudan University Shanghai Cancer Center
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-70 years old for both male and female; 2) With pathologically confirmed colorectal liver metastases; 3) No matter with or without neoadjuvant therapy or conversional therapy; 4) Planned to receive that radical operation for both the primary and liver metastases (both simultaneous or staged surgery accepted); 5) ECOG = 1; 6) Written informed consent signed by patients or their legal representatives can be obtained; 7) With 4-8 ml plasma available; 8) At least 2 years follow-up data available.
Exclusion criteria
Exclusion criteria: 1) Not pathologically confirmed as malignant by colonoscopy or liver biopsy; 2) With AJCC stage of I-III; 3) Diagnosed as stage IV colorectal cancer patients with extrahepatic metastasis; 4) Not able to be radically resected; 5) Withe Blood transfusion performed within 2 weeks before surgery; 6) With any signs of severe or uncontrolled systemic disease which may significantly affect the risk / benefit balance of patients, including uncontrolled hypertension, hepatitis B, hepatitis C, and human immunodeficiency virus; 7) With a history of alcoholism or drug abuse; 8) Pregnant or lactating female patients; 9) Surgical tissue samples not available.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RFS; | — |
Countries
China
Contacts
Public ContactJunjie Peng
Fudan University Shanghai Cancer Center
Outcome results
None listed