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Clinical Study of precise diagnosis and treatment of difficult lung infections based on chest CT screening and metagenomic sequencing as the core of the precise diagnosis and treatment of difficult pulmonary infection

Clinical Study of precise diagnosis and treatment of difficult lung infections based on chest CT screening and metagenomic sequencing as the core of the precise diagnosis and treatment of difficult pulmonary infection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035669
Enrollment
Unknown
Registered
2020-08-16
Start date
2020-10-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary infection

Interventions

Case series:ngs

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
80 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. hospitalized patients >=18 years old; 2. suspected pulmonary infection (excluding tumor, rheumatism, vascular pulmonary disease); 3. no etiological evidence; 4. patients of severe or rapid onset received antiinfective therapy > for more than 2 weeks;patients of chronic onset with anti-infection or course of disease >2 months.

Exclusion criteria

Exclusion criteria: 1. being suspicious of tumor, rheumatic disease or vascular disease; 2. any conditions that may interfere with study procedures and compliance (based on clinician judgment); 3. Subjects refused to submit the relevant body fluid specimen or respiratory tract specimen collection failure; 4. unqualified sequencing data.

Design outcomes

Primary

MeasureTime frame
High throughput sequencing pathogen detection rate of respiratory tract specimens;

Countries

China

Contacts

Public ContactHu Bijie

Zhongshan Hospital, Fudan University

hu.bijie@zs-hospital.sh.cn+86 13601621604

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026