Congenital tracheal stenosis
Conditions
Interventions
GDP group:GDP perfusion strategy
Normal CPB group:Conventional perfusion strategy
Sponsors
Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. RACHS grade 3 or above surgical children; 2. All children with congenital heart disease requiring emergency or subemergency surgery or admitted to ICU before surgery; 3. Gestational age >=32 weeks, weight >=2000g; 4. There was no serious infection before surgery; 5. No history of rescue before surgery.
Exclusion criteria
Exclusion criteria: 1. Severe multiple organ dysfunction syndrome before surgery; 2. Preoperative ECMO/VAD support; 3. Reject THE GDP strategy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Creatinine;urine output;renal area NIRS value;Brain NIRS value;Glial fibrillary acidic protein;Troponin;positive inotropic score;cardiac output inde;ejection fraction;IL-1;IL-2;IL-6;IL-10;TNF-alpha; | — |
Secondary
| Measure | Time frame |
|---|---|
| in-hospital mortality rate;Incidence of complications;Proportion of renal replacement therap;Proportion of auxiliary circulatory use;Ventilator time;ICU time;Delayed chest closure ratio;Length of hospital stay;lactic acid;standard bicarbonate concentration;aminotransferase;Gama - glutamyl transpeptidase; | — |
Countries
Chian
Contacts
Public ContactYinyu Yang
Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University
Outcome results
None listed