large vessel occlusion - stroke
Conditions
Interventions
Group 1:retained balloon catheter
Group 2:Not retained balloon catheter
Sponsors
Shanghai 6th People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. aged 18 to 85 years old; 2. Anterior circulation aortic occlusion is diagnosed by cerebrovascular imaging, the onset time is less than 8h, and patients is evaluated to undergo mechanical thrombectomy surgery; 3. ASPECTS = 6 points (non-enhanced CT), 0 <NIHSS score <30 points (on admission), mRS score <2 points (before the onset), develops clinical symptoms and signs of acute ischemic stroke; 4. Patient who can obtain 2b and 3 levels of recanalization after thrombectomy therapy; 5. The investigator believe that the patient is suitable for receiving an indwelling balloon catheter system to control blood flow and reduce ischemia-reperfusion injury; 6. Patients volunteered to conduct the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients whose life expectancy is less than 3 months; 2. Stroke is accompanied by epilepsy. Patient has a history of intracranial tumors, cerebral arteriovenous malformations, or aneurysms without treatment. Patient has cerebral infarction, myocardial infarction, pulmonary infarction, or uncontrolled severe in the past 3 months Infectious diseases (endocarditis or sepsis, etc.); 3. Patients with coagulation dysfunction or severe heart, liver, kidney dysfunction or systemic infection who are not suitable for interventional therapy; 4. Patients who exclude intracranial parenchymal hematoma by ordinary CT or cone beam CT immediately after operation 5. Patients who participated in clinical trials of other drugs or devices, and has not left the group or withdrawn within 1 month before the screening period of this trial; 6. Patients who have known contraindications to heparin, aspirin, clopidogrel, anesthesia, contrast agents or X-rays.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRS; | — |
Countries
China
Contacts
Public ContactZhu Yueqi
Shanghai 6th People's Hospital
Outcome results
None listed