Tracheal intubation
Conditions
Interventions
Blank:no esketamine
Group A:0.1mg/ kg esketamine (i.v.)
Group B:0.2mg/ kg esketamine (i.v.)
Group C:0.3mg/ kg esketamine (i.v.)
Group D:0.4mg/ kg ?????
Sponsors
Shandong Provincial ENT Hospital, Shandong Provincial Western Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Malampati grade I-II patients with improved difficult airway; 2. ASA grade I-II patients; 3. Patients with laryngeal obstruction grade 1 to 2; 4. Informed consent of patients.
Exclusion criteria
Exclusion criteria: 1. Patients with history of cardiopulmonary disease; 2. Patients with history of diabetes mellitus; 1. Patients with mental history or drug abuse history; 2. Patients with history of chronic pain and self-control of opioids; 3. Patients with severe cardiovascular diseases; 4. Patients with coagulation dysfunction; 5. Patients with allergic history of related drugs; 6. Patients with contraindications of intubation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes of hemodynamic at each time point;changes of blood sugar;OAA/S scares;satisfaction scores for the tracheal intubation process;memory scores for the tracheal intubation process;tolerability scores during tracheal intubation;tolerability scores after tracheal intubation; | — |
Countries
China
Contacts
Public ContactJiyong Wu
Shandong Provincial ENT Hospital, Shandong Provincial Western Hospital
Outcome results
None listed