pulmonary atresia with intact ventricular septum
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. PA/IVS; 2. Aged - 4 and without RVDCC; 4. Preoperative echocardiography showed that cardiac function was more than 60%; 5. B-type natriuretic peptide (BNP) and troponin were normal or slightly abnormal before operation; 6. Good compliance of family members.
Exclusion criteria
Exclusion criteria: 1. There were any other extracardiac malformations and chromosomal abnormalities; 2. Patients with myogenic atresia or severe right ventricular dysplasia or tricuspid valve Z value < - 4 or combined with RVDCC; 3. B-type natriuretic peptide (BNP) and troponin were significantly abnormal before operation; 4. There were obvious neurological symptoms or signs before operation; 5. Patients with low follow-up rate in remote areas; 6. There were contraindications to the use of conventional drugs in the ICU; 7. Patient's unwillingness to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood flow velocity at pulmonary orifice ;liver, kidney function index; | — |
Secondary
| Measure | Time frame |
|---|---|
| cerebral oxygen metabolism;cardiac function index; | — |
Countries
China
Contacts
Shanghai Children's Medical Center