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The application of new EVs markers in accurate diagnosis and treatment of colorectal cancer based on digital PCR technology

The application of new EVs markers in accurate diagnosis and treatment of colorectal cancer based on digital PCR technology

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035608
Enrollment
Unknown
Registered
2020-08-14
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Interventions

Gold Standard:Colonoscopy and tissue case biopsy
Index test:EVs&#32
acid&#32
(miRNA,&#32
lncRNA,&#32
circRNA)&#32
detection&#32

Sponsors

Shanghai Tongji Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. CRC patients admitted to our hospital for initial diagnosis and treatment by colonoscopy and histopathology; 2. Aged 18-75 years male or female; 3. Subjects clearly understand the purpose of the study, are willing and able to comply with the requirements to complete the study, and sign the informed consent; 4. The patient did not receive surgical treatment, in line with the primary CRC diagnostic criteria; 5. All the subjects were examined by medical history, routine physical examination and laboratory examination (including electrocardiogram, Chest X-ray, b-type abdominal ultrasound, liver and kidney function, blood glucose and blood lipid examination, etc.), and all indicators showed normal, excluding other major diseases, recent surgery or malignant tumor diseases.

Exclusion criteria

Exclusion criteria: The patient's tumor has metastasized and cannot be operated on; Other confirmed non-digestive system malignancies; Suffering from other serious diseases that affect the test.

Design outcomes

Primary

MeasureTime frame
RNA;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactLi Dong

Shanghai Tongji Hospital

sunzujun@tongji.edu.cn+86 13611688157

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026