Thyroid associated ophthalmopathy, TAO
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 40-60 years, right handed. 2. Education level >= 5 years, and BMI index, age, gender and education level were matched among the groups. 3. After fully understanding the safety of the research project, willing to actively cooperate with the research and sign the informed consent. 4. Refer to Bartley diagnostic criteria for Tao 5. Diagnostic criteria of Don: Tao patients had the following conditions at the same time: (1) The best corrected visual acuity was less than 20 / 20; (2) Visual field examination showed that the mean defect (MD) value was less than - 5dB; (3) Orbital CT showed orbital apex crowding.
Exclusion criteria
Exclusion criteria: 1. Patients with visual impairment due to refractive media, ametropia, retinal disease, amblyopia, optic atrophy or other non Tao reasons; 2. Color vision abnormality caused by congenital color vision abnormality and other diseases; 3. Patients with history of brain tumor, brain injury or cerebrovascular disease; 4. Patients with nervous system diseases; 5. Patients with poorly controlled diabetes mellitus or severe systemic diseases such as heart, liver and kidney insufficiency; 6. Patients with a history of mental illness or family history; 7. Patients with other metabolic diseases such as diabetes mellitus; 8. Patients who cannot cooperate with CCT due to dark area of visual field center or other factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AO-OCT;CCT;T3, T4, TSH, TRAB; | — |
Secondary
| Measure | Time frame |
|---|---|
| OCT;Orbital CT;Visual Field; | — |
Countries
China
Contacts
Ophthalmology Hospital affiliated to Wenzhou Medical University