Laparoscopic Surgery
Conditions
Interventions
Group 1:lung protection ventilation strategy
Group 2:restrictive hyperventilation
Group 3:PetCO2 dynamic adjustment
Sponsors
Department of Anesthesia and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who undergo elective gastrointestinal surgery laparoscopy; 2. ASA grade I-II grade; 3. Aged 60~80 years; 4. Patients who agree to participate in this trial to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart, brain, liver, lung, kidney and other pathological changes and blood system abnormalities; 2. Pregnant or lactating women; 3. Patients with arrhythmia, valvular heart disease, ischemic heart disease or left ventricular ejection fraction < 40%; 4. Patients with new arrhythmias, arterial intubation failure, or unexpected severe hemodynamic changes during the operation after induction of anesthesia; 5. The operation time is less than 2 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SVV;rSO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Coagulation function;Inflammatory factors;Postoperative pulmonary complications; | — |
Countries
China
Contacts
Public ContactZhisong Li
The Second Affiliated Hospital of Zhengzhou University
Outcome results
None listed