Atopic dermatitis
Conditions
Interventions
Early intervention group:Daily emollient at least once from 3 days after birth until 6 months of age
Long-term intervention group:Daily emollient at least once from 3 days after birth until 12 months of age
Late intervention group:Daily emollient at least once from 21 days after birth until 12 months of age
Non-intervention group:No or irregular use of emollients as needed
Sponsors
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Newborn within 3 days of birth; 2. At least one first-degree relative (parent or sibling) diagnosed with atopic dermatitis, allergic rhinitis or allergic asthma by clinical physician; 3. Postnatal Apgar score at 10; 4. Vital signs stable; 5. Informed consent signed.
Exclusion criteria
Exclusion criteria: 1. Premature infants with gestational age less than 37 weeks; 2. Birth weight less than 2500 g; 3. Severe hereditary skin diseases or primary immunodeficiency diseases that may confuse diagnosis of atopic dermatitis or identification of skin lesions; 4. Poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative prevalence of atopic dermatitis within 1 year of age;Proportion of moderate to severe atopic dermatitis at 1 year of age; | — |
Countries
China
Contacts
Public ContactYAO ZHIRONG
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed