prostate cancer
Conditions
Interventions
Gold Standard:1) Prostate cancer is confirmed by biopsy or puncture pathology
2) The follow-up images of the baseline bone lesions become osteogenic lesions
3) The baseline is soft tissue lesions that meet at least 3 of the following points are also judged as positive. a typical multiple metastases
b lesions enlar
PET/CT
Sponsors
Fudan University Shanghai Cancer Center
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Volunteer to participate and sign informed consent 2. Age = 18 years old 3. Prostate acinar adenocarcinoma and its variants confirmed by puncture or surgical pathology, except for urothelial carcinoma, basal cell carcinoma, small cell carcinoma, etc. 4. Previously received radical treatment of prostate, including radical surgery or radical radiotherapy 5. Meet one or more of the following high-risk prostate cancer criteria: a PSA has been greater than 20 ng/ml; b ISUP is grouped in grade 3-5; c clinical stage T3 or higher 6. Baseline testosterone T<50 ng/dl, serum PSA 0.2-10ng/ml 7. ECOG score 0-1 points 8. The expected survival time is greater than 6 months
Exclusion criteria
Exclusion criteria: 1. Imaging examinations have been performed 4 weeks before randomization. 2. Those who are allergic to iodine contrast agents, have allergies, or are allergic to multiple drugs 3. Before the injection of 18F-FDG, the fasting blood glucose level exceeded 10.0 mmol/L (rapid blood glucose meter test) 4. People with claustrophobia 5. Researchers believe that it is inappropriate to participate in this clinical trial 6. Those who have participated in clinical trials or are participating in other clinical trials in the past month 7. Patients with other malignant tumors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic power; | — |
Secondary
| Measure | Time frame |
|---|---|
| PFS;PSA progress time; | — |
Countries
China
Contacts
Public Contactshaoli song
Outcome results
None listed