Early diagnosis of cardiac surgery-associated acute kidney injury and ischemic preconditioning for prevention of acute kidney injury: a randomized controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000035568

Enrollment

Unknown

Registered

2020-08-13

Start date

2021-05-08

Completion date

Unknown

Last updated

2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute kidney injury

Interventions

Preconditioning group:Remote ischemic preconditioning

Control group:routine regimen

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years; 2. Patients undergoing cardiac surgery scheduled for cardiopulmonary bypass; 3. The risk score of AKI >=4.

Exclusion criteria

Exclusion criteria: 1. Peripheral vascular disease or vascular surgery history of upper limb; 2. The arterial pulsation of the distal upper limb was not obvious; 3. Raynaud's syndrome; 4. Chronic kidney disease, stage 5 (EGFR < 15ml / min / 1.73m2); 5. Acute kidney injury was pre-existing; 6. Gestational period; 7. Kidney transplantation.

Design outcomes

Primary

Measure	Time frame
Serum creatinine;NGAL;KIM-1;TIMP2;	—

Secondary

Measure	Time frame
cTnT;NT-pro-BNP;	—

Countries

China

Contacts

Public ContactPing Jia

Zhongshan Hospital, Fudan University

jia.ping1@zs-hospital.sh.cn+86 13761732850

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026