diabetic peripheral neuropathy
Conditions
Interventions
Intervention group vs drug group:cervical sympathetic nerve regulation therapy
Sponsors
Shanghai 10th People's Hospital,
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40 to 75 years; 2. All meet the diagnostic criteria for diabetes (2014 American Guidelines for Diabetes: Diagnostic criteria for Diabetes); 3. With clinical symptoms and signs of diabetic peripheral neuropathy: numbness, pain, ant walking, burning and cooling in the limbs, which are distributed like gloves and stockings. The patients' sense of touch, pain and warmth are weakened, and the knee-tendon and Achilles tendon reflex are weakened or completely disappeared;Or emG shows multiple peripheral neuropathy; 4. BMI 16-27; 5. Patients voluntarily sign informed consent and can be followed up as scheduled.
Exclusion criteria
Exclusion criteria: 1. Other diseases that cause peripheral neuropathy (cerebral infarction, hyperthyroidism, hypothyroidism, vitamin B12 deficiency, folic acid deficiency, Guillembarr syndrome, cervical disc herniation, lumbar intervertebral disc herniation, vascular disease, radiotherapy, post-chemotherapy, long-term hormone use, sysy-positive, heavy alcohol consumption, etc.); 2. Severe, progressive, uncontrolled diseases of vital organs and systems (including cardiovascular, liver, lung, and kidney), bleeding tendency due to coagulation factor deficiency, autoimmune diseases, malignant tumors, and other diseases that the researchers deem inappropriate to participate in this study; 3. Received sympathetic nerve regulation therapy in recent 3 months; 4. Women who are pregnant, lactating or planning to become pregnant within one year; 5. Received analgesic and anti-inflammatory drugs and anticonvulsant drugs in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS; | — |
Countries
China
Contacts
Public ContactFuqing Lin
Shanghai 10th People's Hospital
Outcome results
None listed