acute on chronic liver failure (ACLF)
Conditions
Interventions
Case series:Nil
Sponsors
Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. chronic liver disease patients, including non-alcoholic fatty liver disease patients, chronic liver hepatitis patients without cirrhosis, compensated cirrhosis patients and decompensated cirrhosis patients; or 2. patients with ALI (alanine aminotransferase or aspartate aminotransferase >3 normal level or total bilirubin >2 normal level within 1 week before enrolment) or AD (ascites, hepatic encephalopathy, bacterial infection or gastrointestinal bleeding within 1 month before enrolment).
Exclusion criteria
Exclusion criteria: 1. non-inpatients (hospitalization 80; 2. hepatocellular carcinoma or other liver malignancies; 3. severe chronic extrahepatic disease; 4. pregnancy; 5. receipt of immunosuppressive drugs for reasons other than chronic.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 90 days mortality of preACLF patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| 90 days mortality of ACLF patients;Time to ACLF development;90 days mortality of non-referal patients; | — |
Countries
China
Contacts
Public ContactHai Li
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Outcome results
None listed