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Preliminary clinical study on non-transecting anastomotic bulbomembranous urethroplasty

Preliminary clinical study on non-transecting anastomotic bulbomembranous urethroplasty

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000035499
Enrollment
Unknown
Registered
2020-08-13
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

urethral stricture

Interventions

1:Reconstruction of urethra after amputation of corpus cavernosum
2:Nontransecting Urethroplasty

Sponsors

Tongji Hospital, Shanghai
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 45 years old; 2. The erectile function of the patients decreased to some extent compared with the normal before operation, but still had certain erectile function (NPT monitoring effective erectile times = 3 times, effective erectile time >= 10 minutes); 3. The levels of androgen (T), estradiol (E2) and pituitary prolactin (PRL) were in the normal range; 4. The length of posterior urethral stricture was estimated to be less than 2.5 cm by urethrography and flexible cystoscopy; 5. There was no history of open urethral surgery; 6. Patients / family members were informed and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. They had a history of open urethral surgery or multiple urethrotomy or urethral dilatation; 2. There was a history of severe hypertension; 3. Have a history of diabetes mellitus; 4. There was a history of coagulation dysfunction or anticoagulant drugs; 5. Patients with liver and kidney insufficiency; 6. Poor compliance; 7. They had mental disorders or neurological dysfunction in the past; 8. Other researchers think it is not suitable to participate in this study.

Design outcomes

Primary

MeasureTime frame
NPT check;??? ??? Qmax;Imaging examination (urethrography);Color Doppler examination of penile blood flow;

Secondary

MeasureTime frame
International erectile function scale;

Countries

China

Contacts

Public ContactCHAO LI

Department of Urology, Tongji Hospital

chaoli1979@126.com+86 15800343081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026