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Study on the diagnostic value of transbronchial lung cryobiopsy combined with rapid on-site evaluation for diffuse lung disease

Study on the value of soft bronchoscopy frozen lung biopsy combined with rapid on-site evaluation in the etiological diagnosis and pathological classification of diffuse lung disease——A prospective, self-controlled observational trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000035492
Enrollment
Unknown
Registered
2020-08-12
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diffuse lung disease

Interventions

Group 1:transbronchial lung biopsy combined with rapid on-site evaluation
Group 2:transbronchial lung cryobiopsy combined with rapid on-site evaluation

Sponsors

Shanghai Pulmonary Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Adult patients aged 18 to 75 years with suspected diagnosis of DLD who require transbronchial lung cryobiopsy; 2. Admitted patients need to complete arterial blood gas analysis, blood routine, blood coagulation routine, liver and kidney function, electrocardiogram, immunological examination, chest HRCT and other examinations; 3. The patients have Good compliance,are able to cooperate with this research observation; 4. Fully inform the purpose and method of the experiment, willing to participate in the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Disagree to participate in this study; 2. Join in other studies, which will affect the observation of this study; 3. Those who fail to cooperate with the completion of the examinations required for admission before bronchoscopy; 4. Those with chest HRCT showing non-interstitial lung disease; 5. The researchers consider that there is any situation that is not suitable for selection.

Design outcomes

Primary

MeasureTime frame
Diagnostic efficiency;specimen size;specimen quality;

Secondary

MeasureTime frame
incidence of bleeding;incidence of pneumothorax;the time of examination;

Countries

China

Contacts

Public ContactKebin Cheng

Department of Respiratory and Critical Care Medicine,Shanghai Pulmonary Hospital

kb.c@163.com+86 13816890251

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026