Ocular indolent non-Hodgkin lymphoma
Conditions
Interventions
1:ultra low-dose radiation group
2:regular dose radiation group
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged >=18 years; 2. Patients with stage I-II ocular MALT or follicular lymphoma involving the conjunctiva, lacrimal gland, oribt soft tissue, extraocular muscle or choroid; 3. Histologically proven follicular or MALT non-Hodgkin's lymphoma; 4. Radiation indicated for definitive treatment of stage I or II disease or for palliation after surgery; 5. Female patients of childbearing potential must have a negative serum pregnancy test (human chorionic gonadotropin [hCG]) within 2 weeks of protocol entry; 6. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with stage III-IV non-Hodgkin's lymphoma; 2. Patients with aggressive B cell lymphoma histology, including diffuse large B cell lymphoma (DLBCL) and mantle cell lymphoma; 3. Patients with severe anemia or mental disorder; 4. Patients who are pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local progression free rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| efficacy;overall survival; | — |
Countries
China
Contacts
Public ContactXiaolu Yang
Shanghai General Hospital
Outcome results
None listed